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John C. Bischof
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Proceedings Papers

A Model of Cryosurgical Destruction in AT-1 Prostate Tumor Based on Cellular Damage Mechanisms

David J. Smith, Sean J. Josephson, John C. Bischof
Proc. ASME. IMECE97, Advances in Heat and Mass Transfer in Biotechnology, 149-150, November 16–21, 1997
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1997-1326
https://doi.org/10.1115/IMECE1997-1326
View Paper titled, A Model of Cryosurgical Destruction in AT-1 Prostate Tumor Based on Cellular Damage Mechanisms
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Topics: Damage, Tumors, Temperature, Wounds, Cooling, Biological tissues, Cancer, Ice, Injury mechanisms, Probability
Proceedings Papers

Measurement of Water Transport During Freezing Using Differential Scanning Calorimetry

Ramachandra V. Devireddy, Debopam Raha, John C. Bischof
Proc. ASME. IMECE96, Advances in Heat and Mass Transfer in Biotechnology, 37-42, November 17–22, 1996
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1996-0748
https://doi.org/10.1115/IMECE1996-0748
View Paper titled, Measurement of Water Transport During Freezing Using Differential Scanning Calorimetry
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Topics: Differential scanning calorimetry, Freezing, Water, Biological tissues, Liver, Cooling, Fittings, Heat, Ice, Microscopy
Proceedings Papers

Supraphysiological Thermal Injury in Dunning AT-1 Prostate Tumor Cells

Sankha Bhowmick, John C. Bischof
Proc. ASME. IMECE98, Advances in Heat and Mass Transfer in Biotechnology, 77-78, November 15–20, 1998
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1998-0798
https://doi.org/10.1115/IMECE1998-0798
View Paper titled, Supraphysiological Thermal Injury in Dunning AT-1 Prostate Tumor Cells
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Topics: Tumors, Wounds, Damage, Membranes, Biological tissues, Temperature, Assaying, Cancer, Dynamics (Mechanics), Leakage
Proceedings Papers

Latent Heat Release in Solute Laden Solutions: Cryobiological Effects

Ramachandra V. Devireddy, John C. Bischof
Proc. ASME. IMECE98, Advances in Heat and Mass Transfer in Biotechnology, 159-161, November 15–20, 1998
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1998-0812
https://doi.org/10.1115/IMECE1998-0812
View Paper titled, Latent Heat Release in Solute Laden Solutions: Cryobiological Effects
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Topics: Biomedicine, Food products, Freezing, Heat, Heat of fusion, Latent heat, Low temperature, Membranes, Modeling, Muscle
Journal Articles

Thermal Analyses of Nanowarming-Assisted Recovery of the Heart From Cryopreservation by Vitrification

Purva Joshi, Lili E. Ehrlich, Zhe Gao, John C. Bischof, Yoed Rabin
Journal: ASME Journal of Heat and Mass Transfer
Publisher: ASME
Article Type: Research-Article
J. Heat Mass Transfer. March 2022, 144(3): 031202.
Paper No: HT-21-1544
https://doi.org/10.1115/1.4053105
Published Online: January 18, 2022
View Article titled, Thermal Analyses of Nanowarming-Assisted Recovery of the Heart From Cryopreservation by Vitrification
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Topics: Boundary-value problems, Containers, Cryonics, Myocardium, Nanoparticles, Temperature, Thermal analysis, Vitrification, Heat transfer, Temperature distribution
Proceedings Papers

Observation of Vascular Injury After Freezing: Investigating the Response of Normal Skin and Subcutaneous AT-1 Tumor Tissue to Cryosurgery in the Dorsal Skin Flap Chamber

Nathan E. Hoffmann, David J. Swanlund, John C. Bischof
Proc. ASME. IMECE99, Advances in Heat and Mass Transfer in Biotechnology, 39-41, November 14–19, 1999
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1999-0579
https://doi.org/10.1115/IMECE1999-0579
View Paper titled, Observation of Vascular Injury After Freezing: Investigating the Response of Normal Skin and Subcutaneous AT-1 Tumor Tissue to Cryosurgery in the Dorsal Skin Flap Chamber
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Topics: Biological tissues, Freezing, Skin, Tumors, Wounds, Crystallization, Damage, Gages, Ice, Osmosis
Proceedings Papers

In Vitro Assessment of the Efficacy of Thermal Therapy in Human Benign Prostatic Hyperplasia Tissue

Sankha Bhowmick, Pragati Bhowmick, James E. Coad, John C. Bischof
Proc. ASME. IMECE2001, Advances in Heat and Mass Transfer in Biotechnology, 125-131, November 11–16, 2001
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2001/HTD-24434
https://doi.org/10.1115/IMECE2001/HTD-24434
View Paper titled, In Vitro Assessment of the Efficacy of Thermal Therapy in Human Benign Prostatic Hyperplasia Tissue
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Topics: Biological tissues, Patient treatment, Temperature, Wounds, Assaying, Heating, Cancer, Copper, Heat treating (Metalworking), Microwaves
Proceedings Papers

Effect of Freezing on Cell Viability and Mechanical Strength of Bioartificial Tissues

Ramachandra V. Devireddy, Michael R. Neidert, John C. Bischof, Robert T. Tranquillo
Proc. ASME. IMECE2001, Advances in Heat and Mass Transfer in Biotechnology, 97-104, November 11–16, 2001
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2001/HTD-24431
https://doi.org/10.1115/IMECE2001/HTD-24431
View Paper titled, Effect of Freezing on Cell Viability and Mechanical Strength of Bioartificial Tissues
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Topics: Biological tissues, Freezing, Strength (Materials), Mechanical properties, Cooling, Failure, Fibroblasts, Stiffness, Tension, Thawing
Proceedings Papers

Evaluation of Freezing Effects on Human Microvascular-Endothelial Cells (hMEC)

Marwane S. Berrada, John C. Bischof
Proc. ASME. IMECE2001, Advances in Heat and Mass Transfer in Biotechnology, 105-113, November 11–16, 2001
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2001/HTD-24432
https://doi.org/10.1115/IMECE2001/HTD-24432
View Paper titled, Evaluation of Freezing Effects on Human Microvascular-Endothelial Cells (hMEC)
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Topics: Freezing, Cooling, Temperature, Ice, Biological tissues, Endothelial cells, Membranes, Nucleation (Physics), Permeability, Shapes
Proceedings Papers

Investigation of Corneal/Scleral Burning During Cataract Surgery

Sankha Bhowmick, John Pedersen, John C. Bischof
Proc. ASME. IMECE2000, Advances in Heat and Mass Transfer in Biotechnology, 73-74, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2224
https://doi.org/10.1115/IMECE2000-2224
View Paper titled, Investigation of Corneal/Scleral Burning During Cataract Surgery
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Topics: Combustion, Cornea, Surgery, Temperature, Damage, Biological tissues, Probes, Ultrasound, Wounds, Computer simulation
Proceedings Papers

Cryo, Hyper or Both? Investigating Combination Cryo/Hyperthermia in the Dorsal Skin Flap Chamber

Nathan E. Hoffmann, Bo H. Chao, John C. Bischof
Proc. ASME. IMECE2000, Advances in Heat and Mass Transfer in Biotechnology, 157-159, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2239
https://doi.org/10.1115/IMECE2000-2239
View Paper titled, Cryo, Hyper or Both? Investigating Combination Cryo/Hyperthermia in the Dorsal Skin Flap Chamber
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Topics: Skin, Patient treatment, Wounds, Biological tissues, Freezing, Cancer, Damage, Diseases, Gages, Radiation (Physics)
Proceedings Papers

Measurement and Modeling of Latent Heat Release During Freezing of Aqueous Solutions in a Small Container

Ramachandra V. Devireddy, John C. Bischof, Perry H. Leo, John S. Lowengrub
Proc. ASME. IMECE2000, Advances in Heat and Mass Transfer in Biotechnology, 23-31, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2217
https://doi.org/10.1115/IMECE2000-2217
View Paper titled, Measurement and Modeling of Latent Heat Release During Freezing of Aqueous Solutions in a Small Container
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Topics: Containers, Freezing, Latent heat, Modeling, Heat, Temperature, Heat of fusion, Ice, Water, Cooling
Proceedings Papers

A Determination of Biophysical Parameters Related to Freezing of an ELT-3 Cell Line

Marwane S. Berrada, John C. Bischof
Proc. ASME. IMECE2000, Advances in Heat and Mass Transfer in Biotechnology, 41-48, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2219
https://doi.org/10.1115/IMECE2000-2219
View Paper titled, A Determination of Biophysical Parameters Related to Freezing of an ELT-3 Cell Line
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Topics: Freezing, Temperature, Cooling, Ice, Water, Biophysics, Damage, Nucleation (Physics), Permeability
Proceedings Papers

Source Terms in Thermal Therapy: A Parametric Study

Sankha Bhowmick, John C. Bischof
Proc. ASME. IMECE2000, Advances in Heat and Mass Transfer in Biotechnology, 161-168, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2240
https://doi.org/10.1115/IMECE2000-2240
View Paper titled, Source Terms in Thermal Therapy: A Parametric Study
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Topics: Patient treatment, Heating, Biological tissues, Lasers, Absorption, Diseases, Heat, Kidney, Liver, Microwave heating
Journal Articles

The Role of Protein Loss and Denaturation in Determining Outcomes of Heating, Cryotherapy, and Irreversible Electroporation on Cardiomyocytes

Feng Liu, Priyatanu Roy, Qi Shao, Chunlan Jiang, Jeunghwan Choi, Connie Chung, Dushyant Mehra, John C. Bischof
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2018, 140(6): 061007.
Paper No: BIO-17-1226
https://doi.org/10.1115/1.4039375
Published Online: April 2, 2018
View Article titled, The Role of Protein Loss and Denaturation in Determining Outcomes of Heating, Cryotherapy, and Irreversible Electroporation on Cardiomyocytes
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Topics: Heating, Proteins, Temperature, Electroporation
Includes: Supplementary data
Journal Articles

Thermomechanical Stress in Cryopreservation Via Vitrification With Nanoparticle Heating as a Stress-Moderating Effect

David P. Eisenberg, John C. Bischof, Yoed Rabin
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2016, 138(1): 011010.
Paper No: BIO-15-1343
https://doi.org/10.1115/1.4032053
Published Online: December 8, 2015
View Article titled, Thermomechanical Stress in Cryopreservation Via Vitrification With Nanoparticle Heating as a Stress-Moderating Effect
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Topics: Cryonics, Heating, Nanoparticles, Stress, Temperature, Thermomechanics, Vitrification, Cooling, Heat transfer, Crystallization
Proceedings Papers

Biodistribution of TNF-alpha Coated Gold Nanoparticles in an In Vivo Cancer Model

Raghav Goel, Neha Shah, Rachana Visaria, Giulio F. Paciotti, John C. Bischof
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 831-832, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192931
https://doi.org/10.1115/SBC2008-192931
View Paper titled, Biodistribution of TNF-alpha Coated Gold Nanoparticles in an In Vivo Cancer Model
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Topics: Cancer, Nanoparticles, Patient treatment, Biological tissues, Heat
Proceedings Papers

Multi-Probe Cryosurgical Configurations Extract Significantly Less Energy per Probe Than Single Probe Configurations: Implications for Clinical Cryosurgery

Xiaoqing Zhang, Christoph Leng, Mithun M. Shenoi, John C. Bischof
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 631-632, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193088
https://doi.org/10.1115/SBC2008-193088
View Paper titled, Multi-Probe Cryosurgical Configurations Extract Significantly Less Energy per Probe Than Single Probe Configurations: Implications for Clinical Cryosurgery
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Topics: Probes, Cooling, Separation (Technology)
Proceedings Papers

Use of Raman Microspectroscopy to Study Partioning of Molecules During Freeze-Processing of Protein Solutions

Jinping Dong, Allison Hubel, John C. Bischof, Alptekin Aksan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 905-906, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193052
https://doi.org/10.1115/SBC2008-193052
View Paper titled, Use of Raman Microspectroscopy to Study Partioning of Molecules During Freeze-Processing of Protein Solutions
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Topics: Cooling, Cryonics, Crystallization, Freezing, Ice, Latent heat, Microspectroscopy, Phase separation, Proteins, Temperature gradient
Proceedings Papers

Effects of Glycerol on the Thermal Properties of Phosphate Buffered Saline and Porcine Liver at Subzero Temperatures

Jeung H. Choi, John C. Bischof
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 85-86, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176561
https://doi.org/10.1115/SBC2007-176561
View Paper titled, Effects of Glycerol on the Thermal Properties of Phosphate Buffered Saline and Porcine Liver at Subzero Temperatures
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Topics: Liver, Temperature, Thermal properties, Performance, Biological tissues, Cryonics, Crystallization, Databases, Dimensions, Ice