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Journal Articles

svMorph: Interactive Geometry-Editing Tools for Virtual Patient-Specific Vascular Anatomies

Jonathan Pham, Sofia Wyetzner, Martin R. Pfaller, David W. Parker, Doug L. James, Alison L. Marsden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2023, 145(3): 031001.
Paper No: BIO-22-1143
https://doi.org/10.1115/1.4056055
Published Online: December 5, 2022
View Article titled, svMorph: Interactive Geometry-Editing Tools for Virtual Patient-Specific Vascular Anatomies
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Topics: Aneurysms, Engineering simulation, Geometry, Hemodynamics, Shapes, Simulation, Deformation, Aorta, Computational fluid dynamics, Modeling
Journal Articles

Integrated Image-Based Computational Fluid Dynamics Modeling Software as an Instructional Tool

Kimberly A. Stevens Boster, Melody Dong, Jessica M. Oakes, Chiara Bellini, Vitaliy L. Rayz, John F. LaDisa, Jr., Dave Parker, Nathan M. Wilson, Shawn C. Shadden, Alison L. Marsden, Craig J. Goergen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2020, 142(11): 111008.
Paper No: BIO-20-1136
https://doi.org/10.1115/1.4047479
Published Online: September 9, 2020
View Article titled, Integrated Image-Based Computational Fluid Dynamics Modeling Software as an Instructional Tool
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Topics: Computational fluid dynamics, Computer software, Modeling, Simulation, Students, Cardiovascular system, Boundary-value problems, Diseases
Journal Articles

A Re-Engineered Software Interface and Workflow for the Open-Source SimVascular Cardiovascular Modeling Package

Hongzhi Lan, Adam Updegrove, Nathan M. Wilson, Gabriel D. Maher, Shawn C. Shadden, Alison L. Marsden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2018, 140(2): 024501.
Paper No: BIO-17-1574
https://doi.org/10.1115/1.4038751
Published Online: January 25, 2018
View Article titled, A Re-Engineered Software Interface and Workflow for the Open-Source SimVascular Cardiovascular Modeling Package
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Topics: Cardiovascular system, Computer software, Graphical user interfaces, Image segmentation, Modeling, Simulation, Vessels, Pipelines, Visualization, Boundary-value problems
Journal Articles

Multiscale Modeling of Cardiovascular Flows for Clinical Decision Support

Alison L. Marsden, Mahdi Esmaily-Moghadam
Journal: Applied Mechanics Reviews
Publisher: ASME
Article Type: Review Articles
Appl. Mech. Rev. May 2015, 67(3): 030804.
Paper No: AMR-14-1063
https://doi.org/10.1115/1.4029909
Published Online: May 1, 2015
View Article titled, Multiscale Modeling of Cardiovascular Flows for Clinical Decision Support
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Topics: Cardiovascular system, Flow (Dynamics), Multiscale modeling, Physiology, Simulation, Modeling, Pressure, Engineering simulation, Vessels, Surgery
Journal Articles

Computational Simulation of the Adaptive Capacity of Vein Grafts in Response to Increased Pressure

Abhay B. Ramachandra, Sethuraman Sankaran, Jay D. Humphrey, Alison L. Marsden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2015, 137(3): 031009.
Paper No: BIO-14-1128
https://doi.org/10.1115/1.4029021
Published Online: March 1, 2015
View Article titled, Computational Simulation of the Adaptive Capacity of Vein Grafts in Response to Increased Pressure
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Topics: Pressure, Stress, Simulation, Vessels
Proceedings Papers

Evaluation of Hemodynamic Efficiency in a New “Y-Graft” Design for the Fontan Operation

Adam J. Bernstein, Alison L. Marsden, Ryan L. Spilker, V. Mohan Reddy, Charles A. Taylor, Jeffrey A. Feinstein
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 473-474, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176279
https://doi.org/10.1115/SBC2007-176279
View Paper titled, Evaluation of Hemodynamic Efficiency in a New “Y-Graft” Design for the Fontan Operation
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Topics: Blood flow, Design, Hemodynamics, Junctions, Pulmonary artery
Proceedings Papers

Patient-Specific Hemodynamic Simulations in a Group of Patients With Coronary Artery Aneurysms Caused by Kawasaki Disease

Dibyendu Sengupta, Jane C. Burns, Andrew Kahn, Alison L. Marsden
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT11A006, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14842
https://doi.org/10.1115/SBC2013-14842
View Paper titled, Patient-Specific Hemodynamic Simulations in a Group of Patients With Coronary Artery Aneurysms Caused by Kawasaki Disease
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Topics: Aneurysms, Coronary arteries, Diseases, Engineering simulation, Hemodynamics, Simulation, Computational fluid dynamics, Risk, Thrombosis, Anatomy
Proceedings Papers

Growth and Remodeling of Vein Graft in an Arterial Environment: Parameter Estimation and Sensitivity Analysis

Abhay B. Ramachandra, Sethuraman Sankaran, Jay D. Humphrey, Alison L. Marsden
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT28A009, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14617
https://doi.org/10.1115/SBC2013-14617
View Paper titled, Growth and Remodeling of Vein Graft in an Arterial Environment: Parameter Estimation and Sensitivity Analysis
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Topics: Blood vessels, Coronary arteries, Design, Diseases, Failure, Flow (Dynamics), Geometry, Hemodynamics, High pressure (Physics), Parameter estimation
Proceedings Papers

A Computational Technique for Uncertainty Quantification and Robust Design in Cardiovascular Systems

Sethuraman Sankaran, Jeffrey A. Feinstein, Alison L. Marsden
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 17-18, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-204873
https://doi.org/10.1115/SBC2009-204873
View Paper titled, A Computational Technique for Uncertainty Quantification and Robust Design in Cardiovascular Systems
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Topics: Cardiovascular system, Design, Uncertainty quantification, Uncertainty, Blood flow, Inflow, Surgery, Engineering simulation, Geometry, Simulation
Proceedings Papers

A Computational Investigation of Murray’s Law Using 3-D Navier Stokes Solutions and Derivative-Free Optimization

Dibyendu Sengupta, Alison L. Marsden
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 473-474, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206879
https://doi.org/10.1115/SBC2009-206879
View Paper titled, A Computational Investigation of Murray’s Law Using 3-D Navier Stokes Solutions and Derivative-Free Optimization
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Topics: Optimization, Bifurcation, Vessels, Flow (Dynamics), Pressure
Proceedings Papers

Optimization of an Idealized Y-Graft for the Fontan Procedure Using CFD and a Derivative-Free Optimization Algorithm

Weiguang Yang, Jeffrey A. Feinstein, V. Mohan Reddy, Alison L. Marsden
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 449-450, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206492
https://doi.org/10.1115/SBC2009-206492
View Paper titled, Optimization of an Idealized Y-Graft for the Fontan Procedure Using CFD and a Derivative-Free Optimization Algorithm
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Topics: Computational fluid dynamics, Hemodynamics, Junctions, Optimization, Optimization algorithms, Proteins, Pulmonary artery, Surgery
Proceedings Papers

Comparison of Clinical and Simulation Results for the Stanford Y-Graft Fontan Pilot Trial

Weiguang Yang, Jeffrey A. Feinstein, V. Mohan Reddy, Frandics P. Chan, Alison L. Marsden
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 463-464, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80928
https://doi.org/10.1115/SBC2012-80928
View Paper titled, Comparison of Clinical and Simulation Results for the Stanford Y-Graft Fontan Pilot Trial
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Topics: Blood, Maintenance, Pulmonary artery, Simulation results, Surgery, Tunnels
Proceedings Papers

Multiscale Model of Airflow in Healthy and Emphysema Rat Lungs

Jessica M. Oakes, Alison L. Marsden, Celine Grandmont, Chantal Darquenne, Irene E. Vignon-Clementel
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1263-1264, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80418
https://doi.org/10.1115/SBC2012-80418
View Paper titled, Multiscale Model of Airflow in Healthy and Emphysema Rat Lungs
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Topics: Air flow, Lung, Aerosols, Biological tissues, Computer simulation, Diseases, Dynamics (Mechanics), Oxygen, Particulate matter, Ventilation
Proceedings Papers

Customization of the Fontan Y-Graft: Are Unequal Branches Necessary for Optimal Hepatic Flow Distribution?

Weiguang Yang, Jeffrey A. Feinstein, Irene E. Vignon-Clementel, Shawn C. Shadden, Alison L. Marsden
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 461-462, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53752
https://doi.org/10.1115/SBC2011-53752
View Paper titled, Customization of the Fontan Y-Graft: Are Unequal Branches Necessary for Optimal Hepatic Flow Distribution?
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Topics: Diseases, Flow (Dynamics), Junctions, Liver, Pulmonary artery, Surgery
Proceedings Papers

Comparison of Normal and Pathological Hemodynamics in Coronary Artery Aneurysms Caused by Kawasaki Disease

Dibyendu Sengupta, Jane C. Burns, Andrew Kahn, Alison L. Marsden
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 269-270, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53864
https://doi.org/10.1115/SBC2011-53864
View Paper titled, Comparison of Normal and Pathological Hemodynamics in Coronary Artery Aneurysms Caused by Kawasaki Disease
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Topics: Aneurysms, Coronary arteries, Diseases, Hemodynamics, Blood flow, Engineering simulation, Risk, Risk assessment, Simulation, Thrombosis
Proceedings Papers

A Coupled Computational Framework for Multiscale Modeling and Optimization of Single Ventricle Repair

Alison L. Marsden, Mahdi Esmaily Moghadam, Weiguang Yang, Alessia Baretta, Chiara Corsini, Irene Vignon-Clementel, Francesco Migliavacca, Jeffrey Feinstein, Tain-Yen Hsia
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 519-520, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53759
https://doi.org/10.1115/SBC2011-53759
View Paper titled, A Coupled Computational Framework for Multiscale Modeling and Optimization of Single Ventricle Repair
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Topics: Maintenance, Multiscale modeling, Optimization, Surgery, Boundary-value problems, Cardiovascular system, Finite element model, Geometry, Hemodynamics
Proceedings Papers

Image-Based Morphometry and Airflow Simulation in Rat Lungs

Jessica M. Oakes, Alison L. Marsden, Miriam Scadeng, Chantal Darquenne
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 655-656, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19561
https://doi.org/10.1115/SBC2010-19561
View Paper titled, Image-Based Morphometry and Airflow Simulation in Rat Lungs
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Topics: Air flow, Lung, Simulation, Flow (Dynamics), Aerosols, Boundary-value problems, Pressure, Drugs, Flow simulation, Magnetic resonance
Proceedings Papers

Patient-Specific Hemodynamic Simulations in Coronary Artery Aneurysms Caused by Kawasaki Disease

Dibyendu Sengupta, Jane C. Burns, Andrew Kahn, Alison L. Marsden
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 575-576, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19591
https://doi.org/10.1115/SBC2010-19591
View Paper titled, Patient-Specific Hemodynamic Simulations in Coronary Artery Aneurysms Caused by Kawasaki Disease
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Topics: Aneurysms, Coronary arteries, Diseases, Engineering simulation, Hemodynamics, Simulation, Blood flow, Pediatrics, Risk, Risk assessment
Proceedings Papers

CFD Simulation of Flow Mixing in the Vertobrobasilar System

Matthew D. Bockman, Akash P. Kansagra, Eric C. Wong, Alison L. Marsden
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 679-680, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19706
https://doi.org/10.1115/SBC2010-19706
View Paper titled, CFD Simulation of Flow Mixing in the Vertobrobasilar System
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Topics: Computational fluid dynamics, Flow (Dynamics), Simulation, Vessels, Blood, Brain, Cerebral arteries, Hemodynamics, Imaging, Magnetic resonance imaging
Proceedings Papers

Virtual Design for the Fontan Procedure: From Idealized to Patient Specific Models Using CFD and Derivative-Free Optimization

Weiguang Yang, Guillaume Troianowski, Alexandre Birolleau, Irene Vignon-Clementel, Jeffrey A. Feinstein, Alison L. Marsden
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 425-426, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19683
https://doi.org/10.1115/SBC2010-19683
View Paper titled, Virtual Design for the Fontan Procedure: From Idealized to Patient Specific Models Using CFD and Derivative-Free Optimization
Open the PDF for Virtual Design for the Fontan Procedure: From Idealized to Patient Specific Models Using CFD and Derivative-Free Optimization in another window
Topics: Computational fluid dynamics, Design, Junctions, Modeling, Optimization, Pediatrics, Pulmonary artery, Surgery