In the present study, replication of flow-through microfilters in the newly developed microfluidic lab-on-a-chip for blood typing by microinjection molding process was experimentally investigated. As a precise replication of the microfilters was required in order to effectively filter out agglutinated red blood cells, the effects of important processing conditions on the replication of the flow-through microfilters were investigated. By using a mold insert fabricated by a nickel electroplating process and a newly designed mold base, microinjection molding experiments were carried out. A three-dimensional solid model reconstruction method was proposed with the help of specific features characterizing the geometry of microfilters, and accordingly, the feature values of the replicated microfilters were measured by a noncontact optical measurement system. So reconstructed solid modeling result was then used to investigate the effects of various processing conditions, such as a flow rate, a mold temperature, and a packing pressure. Amongst the processing conditions investigated in the present study, the flow rate was found to be the most important one.
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e-mail: smkds@cau.ac.kr
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April 2008
Research Papers
Replication Quality of Flow-Through Microfilters in Microfluidic Lab-on-a-Chip for Blood Typing by Microinjection Molding
Bong-Kee Lee,
Bong-Kee Lee
Department of Mechanical Engineering,
Pohang University of Science and Technology (POSTECH)
, San 31, Hyoja-Dong, Nam-Gu, Pohang, Gyungbuk 790-784, Korea
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Chul Jin Hwang,
Chul Jin Hwang
Precision Mold Technology Team,
Korea Institute of Industrial Technology (KITECH)
, 193 Yakdae-Dong, Wonmi-Gu, Buchen, Gyeonggi-Do 420-734, Korea
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Dong Sung Kim,
Dong Sung Kim
School of Mechanical Engineering,
e-mail: smkds@cau.ac.kr
Chung-Ang University
, 221 Heukseok-Dong, Dongjak-Gu, Seoul 156-756, Korea
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Tai Hun Kwon
Tai Hun Kwon
Department of Mechanical Engineering,
e-mail: thkwon@postech.ac.kr
Pohang University of Science and Technology (POSTECH)
, San 31, Hyoja-Dong, Nam-Gu, Pohang, Gyungbuk 790-784, Korea
Search for other works by this author on:
Bong-Kee Lee
Department of Mechanical Engineering,
Pohang University of Science and Technology (POSTECH)
, San 31, Hyoja-Dong, Nam-Gu, Pohang, Gyungbuk 790-784, Korea
Chul Jin Hwang
Precision Mold Technology Team,
Korea Institute of Industrial Technology (KITECH)
, 193 Yakdae-Dong, Wonmi-Gu, Buchen, Gyeonggi-Do 420-734, Korea
Dong Sung Kim
School of Mechanical Engineering,
Chung-Ang University
, 221 Heukseok-Dong, Dongjak-Gu, Seoul 156-756, Koreae-mail: smkds@cau.ac.kr
Tai Hun Kwon
Department of Mechanical Engineering,
Pohang University of Science and Technology (POSTECH)
, San 31, Hyoja-Dong, Nam-Gu, Pohang, Gyungbuk 790-784, Koreae-mail: thkwon@postech.ac.kr
J. Manuf. Sci. Eng. Apr 2008, 130(2): 021010 (8 pages)
Published Online: March 25, 2008
Article history
Received:
July 24, 2007
Revised:
January 8, 2008
Published:
March 25, 2008
Citation
Lee, B., Hwang, C. J., Kim, D. S., and Kwon, T. H. (March 25, 2008). "Replication Quality of Flow-Through Microfilters in Microfluidic Lab-on-a-Chip for Blood Typing by Microinjection Molding." ASME. J. Manuf. Sci. Eng. April 2008; 130(2): 021010. https://doi.org/10.1115/1.2896142
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