...Luke Nigro; Elisa S. Arch Natural ankle quasi-stiffness (NAS) is a mechanical property of the ankle joint during dynamic motion. NAS has been historically calculated as the average slope (linear regression) of the net ankle moment versus ankle angle during discrete phases of stance. However, recent...

.../1.3212104 annulus fibrosus intervertebral disc biomechanics tensile properties stiffness Natural Sciences and Engineering Research Council of Canada 10.13039/501100000038 RGPIN-2020-04723 The number one cause of disability worldwide is low back pain [ 1 ], often the result...

...@uscmed.sc.edu e-mail:  jay.humphrey@yale.edu 17 05 2021 14 10 2021 15 12 2021 hypertension Marfan syndrome extracellular matrix remodeling stiffness phenotype National Institutes of Health 10.13039/100000002 R01 HL145064 National Science Foundation 10.13039...

... SPARC-null (n = 36) and WT (n = 18) mice aged 14–25 months were subjected to cyclic axial tension and compression to determine neutral zone (NZ) length and stiffness. Three separate mechanical tests were completed for each spine to determine the effect of the number of IVDs tested in series (one versus...

... pathological development in the cells; pathological or aging cells, on the other hand, can alter their micro-environment to become abnormal. In this minireview, we discuss four important biophysical cues of the micro-environment—stiffness, curvature, extracellular matrix (ECM) architecture and viscosity...

...Alex M. Noonan; Derek P. Zwambag; Nicole Mazara; Erin Weersink; Geoffrey A. Power; Stephen H. M. Brown Studies on single muscle fiber passive material properties often report relatively large variation in elastic modulus (or normalized stiffness), and it is not clear where this variation arises...

... . 10.1016/j.mri.2011.12.019 [14] Murphy , M. C. , Huston , J. , Jack , C. R. , Glaser , K. J. , Manduca , A. , Felmlee , J. P. , and Ehman , R. L. , 2011 , “ Decreased Brain Stiffness in Alzheimer's Disease Determined by Magnetic Resonance...

..., HR-pQCT scans were performed on the standard scan segment, a segment distal to the standard segment, and a segment proximal to the standard segment. Whole distal radius and tibia stiffness were determined through mechanical testing. Segment bone stiffness was estimated using linear finite element (FE...

... and measurement methods, so it is not surprising that they produce different results. The mechanical properties of skin tissues are dependent on the loading direction [ 16 ]; the air-jet machine provides measurements of stiffness perpendicular to the surface of the skin within the physiologic limit, while...

..., trabecular anisotropy on QCT-based FE predictions of vertebral stiffness and deformation patterns. Orthotropic material properties estimated from microcomputed tomography data (“specimen-specific anisotropy”), were assigned to a large, columnar region of the L1 centrum ( n  = 12), and generic-anisotropic...

... bending from 50 N to 300 N at 1 Hz for 25 cycles. All femurs were tested in both anteroposterior (AP) and mediolateral (ML) bending planes. Bending stiffness (i.e., slope of the force-vs-displacement curve) and linearity R 2 (i.e., coefficient of determination) of each loading cycle were measured...

... portion of the third cycle was used to measure the stiffness. Indentation tests were performed on two polyurethane foams and polymethyl-methacrylate for validation ( n = 15 ) . Regression analysis was used to compare the moduli with reference values. Subchondral bone moduli of tibial plateaus from Sprague...

... spinal segments (Occiput-C2, C4-C5, and C6-C7) for measurement of tensile structural response and failure testing. The upper cervical spine (Occiput-C2) was found to be significantly less stiff, absorb less strain energy, and fail at higher loads than the lower cervical spine (C4-C5 and C6-C7...

... and the force acting on the needles. This relationship allows the force on the microneedle to be determined from a known field gradient. This together with a measurement of the displacement of the needle in a given gel allows one to determine the stiffness ( F ∕ δ ) of the gel and the elastic modulus, provided...

... of mixtures for fiber composites to evaluate the dependence of age-related changes in tendon tensile strength ( σ ) and stiffness ( E ) on the collagen fibril cross-sectional area fraction ( ρ ) , which is related to the fibril volume fraction. Tail tendons from C57BL6 mice from age groups 1.6 – 35.3 months...

... brain stiffness Characterization of tissue material properties is important in a number of ways to medical clinicians and researchers. Changes in material stiffness can indicate the presence of tumors and other diseases ( 1 ). In the case of deep venous thrombosis (DVT), hardness...

...-brittle transition stiffness strength In a failure scenario, bone will often have been exposed to high strain rates. From equine and canine studies using surgically implanted strain gauges, Rubin et al. ( 1 ) concluded that physiological strain rates during walking and running are in the range...

... biomembranes finite element analysis cataracts accommodation biomechanics stress stiffness Despite the widely recognized importance of the biomechanics of the lens capsule in normal processes such as accommodation and clinical interventions such as cataract surgery, there has been no prior...

...J. A. Simo˜es; J. Monteiro; M. A. Vaz The aim of this paper is to describe a new numerical–experimental method to determine the stiffness of a conceptual proximal femoral prototype. The methodology consists of the comparison of the numerical and experimental displacement distributions...