...). This gives surgeons more freedom when implanting the valve but it also results in uncertainties regarding placement, particularly with respect to valve orientation. We investigate the pulmonary artery hemodynamics and valve leaflet dynamics of pulmonary valve replacements (PVRs) with various orientations via...

...Li Changsheng; Feng Haiquan; Wang Kun; Wang Xiaotian; Wang Yonggang Few reports study the effects of the anatomical structure of the iliac vein on hemodynamics and the methods to reduce and delay in-stent thrombosis. The anatomical structure of iliac vein stenosis was used to establish vascular...

...Christian J. Mandrycky; Ashley N. Abel; Samuel Levy; Laurel M. Marsh; Fanette Chassagne; Venkat K. Chivukula; Sari E. Barczay; Cory M. Kelly; Louis J. Kim; Alberto Aliseda; Michael R. Levitt; Ying Zheng Hemodynamic factors have long been associated with clinical outcomes in the treatment...

... computational fluid dynamics (CFD). First, the hemodynamics environment in the iliac arterial tree considering a large network of bifurcations was studied. The results showed complex blood flow patterns in the iliac arterial network. Subsequently, the transport of embolic particulates during PAE...

.... The effect of PFS intervention on the hemodynamic efficiency is estimated by all of the significant criteria used for the evaluation of aneurysm occlusion and possible rupture; the flow velocity, pressure, wall shear stress (WSS), and WSS-related indices. Results showed that PFS intervention preserves...

... with measured blood flow velocity waveforms in the common iliac arteries (with each body posture being maintained for 30 min) to build computational models for simulating intra-arterial hemodynamics. Morphological analyses showed that the external iliac arteries suffered from evident bending deformation upon...

... using a computational approach on a patient-specific basis under fully pulsatile hemodynamics with a multiscale computational fluid dynamics model incorporating a coupled Eulerian-Lagrangian scheme that effectively tracks emboli in the fluid domain. Blood is modeled as a non-Newtonian fluid based...

... might influence coronary hemodynamics and solid mechanics differently. Computational modeling could be used to quantify biomechanical conditions under which patients could receive patient-specific treatment plan with optimized outcome after antithrombotic therapy. More patient studies with follow-up...

... of aneurysms are treated with the same patient-specific endovascular coils. Synchrotron tomography scans of the coil mass morphology are obtained. Aneurysmal hemodynamics are computationally simulated before and after coiling, using patient-specific velocity/pressure measurements. For each patient, we analyze...

... and compare different mechanotransduction and biotransport mechanisms. e-mail:  amir.arzani@nau.edu 22 06 2020 07 10 2020 14 12 2020 Coronary artery disease biochemical transport Lagrangian coherent structures mechanotransduction endothelial cells hemodynamics...

... and delayed remodeling of the local vasculature. Recent studies have demonstrated that this phenomenon may assume different roles depending on the treatment stage. However, the extent of such event on the intra-aneurysmal hemodynamics is still unclear; especially when performing two-step stent-assisted...

.... The results of this study suggest that integrated CFD software can be a helpful tool to teach hemodynamic and patient-specific modeling principles. Even though previous reports have described interactive educational resources for simulation-based teaching and learning [ 9 – 11 ], integrated CFD software...

... separation were found to be significant contributions to accurate reduce order modeling of transstenotic coronary hemodynamics. 1 Corresponding author. 2 Technically, FFR = ( P dist − P v / P ao − P v ), although central venous pressure ( P v  < 8 mmHg) is often assumed negligible...

...; published online December 12, 2018. Assoc. Editor: Keefe B. Manning. 18 05 2018 08 11 2018 computational fluid dynamics (CFD) hemodynamics blood trauma hemolysis shear stress mesh sensitivity wall functions ventricular assist device (VAD) Despite extensive research...

... differences from the real flow. It also should note that there are numerous factors that cause diastolic dysfunction, such as LV hypertrophy, LV dilatation, pericarditis, etc. Each single pathological condition could yield differences in terms of hemodynamics and blood mixing. However, one common feature...

... WSS, less blood stagnation area, and better blood flow close to the artery wall. From the viewpoint of the combination of solid mechanics and hemodynamics, the S-stent has better therapeutic effects because of its lower potential for inducing ISR and its better prospects in clinical...

... , “ Echocardiographic Recognition of the Congenital Bicuspid Aortic Valve ,” Circulation , 49 ( 5 ), pp. 870 – 875 . 10.1161/01.CIR.49.5.870 [11] Barker , A. J. , and Markl , M. , 2011 , “ The Role of Hemodynamics in Bicuspid Aortic Valve Disease ,” Eur. J. Cardiothorac. Surg. , 39 ( 6 ), pp. 805...

... adjust blood viscosity and, consequently, flow resistance, which is relevant for hemodynamic simulations. The parametric descriptions of these effects, which consider the thickness of the endothelial surface layer (ESL), were derived from experiments in previous studies [ 45 ] and are given...

... the nonlinear heterogeneous mechanical properties of both the ILT and aneurysmal wall, preferably including constituent specific correlations with histological characteristics as a lesion evolves. (ii) Thrombus deposition and evolution—identify criteria that govern the initial and subsequent hemodynamically...

..., 2013; accepted manuscript posted January 18, 2013; published online February 7, 2013. Editor: Victor H. Barocas. 03 10 2012 06 01 2013 18 01 2013 Studies investigating the relation between the focal nature of atherosclerosis and hemodynamic factors are employing increasingly...