... in this review, with discussion of binding selectivity and targeting performance for these peptide sequences where possible. Aptamers are RNA or DNA strands evolutionarily engineered to specifically bind a chosen target. Although use of aptamers in targeted delivery is a relatively new avenue of research...

.... In this study, a mass-action based model has been developed to investigate the effect of Au nanoparticles on the two-round PCR results. The great affinity of Au nanoparticles to the single-stranded DNA is taken into consideration. Each nanoparticle is treated as a bioreactor and/or a selector, around which...

... the stretch-activated cation channel blocker gadolinium chloride, the L -type voltage-activated calcium channel blocker nicardipine, the c-jun N H 2 -terminal kinase (JNK) blocker D-JNK inhibitor 1, and the calpain inhibitor MDL 28170. Apoptosis was assessed through DNA fragmentation using the terminal...

... are significant for medium dimensions up to several times those of the inclusion. Application of the method to DNA-crosslinked gels showed good agreement with direct compression tests. 18 03 2004 23 02 2005 biomedical materials DNA molecular biophysics polymer gels nondestructive testing...

... map showed that the nucleus experiences stress on the order of magnitude that can be significant for the function of DNA molecules and chromatin fibers. This study of endothelial cell mechanobiology suggests the possibility that mechanotransduction could result, in part, from nuclear deformation...

...David C. Lin; Bernard Yurke; Noshir A. Langrana Mechanical properties of a polyacrylamide gel with reversible DNA crosslinks are presented. In this system, three DNA strands replace traditional chemical crosslinkers. In contrast to thermoset chemically crosslinked polyacrylamide, the new hydrogel...

...David L. Butler; Steven A. Goldstein; Farshid Guilak “Tissue engineering” uses implanted cells, scaffolds, DNA, protein, and/or protein fragments to replace or repair injured or diseased tissues and organs. Despite its early success, tissue engineers have faced challenges in repairing or replacing...