Microimaging based finite element analysis is widely used to predict the mechanical properties of trabecular bone. The choice of thresholding technique, a necessary step in converting grayscale images to finite element models, can significantly influence the predicted bone volume fraction and mechanical properties. Therefore, we investigated the effects of thresholding techniques on microcomputed tomography (micro-CT) based finite element models of trabecular bone. Three types of thresholding techniques were applied to 16-bit micro-CT images of trabecular bone to create three different models per specimen. Bone volume fractions and apparent moduli were predicted and compared to experimental results. In addition, trabecular tissue mechanical parameters and morphological parameters were compared among different models. Our findings suggest that predictions of apparent mechanical properties and structural properties agree well with experimental measurements regardless of the choice of thresholding methods or the format of micro-CT images.
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e-mail: chihyun@yonsei.ac.kr
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August 2007
Technical Papers
Effects of Thresholding Techniques on -Based Finite Element Models of Trabecular Bone
Chi Hyun Kim,
Chi Hyun Kim
Department of Biomedical Engineering, Institute of Medical Engineering,
e-mail: chihyun@yonsei.ac.kr
Yonsei University
, 234 Maejiri, Wonju, Kangwon Do, Korea
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Henry Zhang,
Henry Zhang
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027
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George Mikhail,
George Mikhail
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027
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Dietrich von Stechow,
Dietrich von Stechow
Beth Israel Deaconess Medical Center and Harvard Medical School
, Boston, MA 02215
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Ralph Müller,
Ralph Müller
Beth Israel Deaconess Medical Center and Harvard Medical School
, Boston, MA 02215
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Han Sung Kim,
Han Sung Kim
Department of Biomedical Engineering, Institute of Medical Engineering,
Yonsei University
, 234 Maejiri, Wonju, Kangwon Do, Korea
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X. Edward Guo
X. Edward Guo
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027
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Chi Hyun Kim
Department of Biomedical Engineering, Institute of Medical Engineering,
Yonsei University
, 234 Maejiri, Wonju, Kangwon Do, Koreae-mail: chihyun@yonsei.ac.kr
Henry Zhang
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027
George Mikhail
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027
Dietrich von Stechow
Beth Israel Deaconess Medical Center and Harvard Medical School
, Boston, MA 02215
Ralph Müller
Beth Israel Deaconess Medical Center and Harvard Medical School
, Boston, MA 02215
Han Sung Kim
Department of Biomedical Engineering, Institute of Medical Engineering,
Yonsei University
, 234 Maejiri, Wonju, Kangwon Do, Korea
X. Edward Guo
Department of Biomedical Engineering,
Columbia University
, New York, NY 10027J Biomech Eng. Aug 2007, 129(4): 481-486 (6 pages)
Published Online: December 20, 2006
Article history
Received:
October 19, 2005
Revised:
December 20, 2006
Citation
Kim, C. H., Zhang, H., Mikhail, G., Stechow, D. V., Müller, R., Kim, H. S., and Guo, X. E. (December 20, 2006). "Effects of Thresholding Techniques on -Based Finite Element Models of Trabecular Bone." ASME. J Biomech Eng. August 2007; 129(4): 481–486. https://doi.org/10.1115/1.2746368
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